Two very interesting stories making headlines in the past couple of days. One of the largest studies into the effects of MDMA (3,4-Methylenedioxymethamphetamine, made popular in the form of ecstasy pills) to date has found that there is no evidence that the drug causes brain damage, and that it’s danger’s have been greatly exaggerated.
The Guardian article concludes with Professor John Halpern of Harvard Medical School saying “Ecstasy consumption is dangerous because illegally made pills often contain contaminants that can have harmful side-effects.”
Well that’s funny. You’d think the logical conclusion would be to regulate and legalize MDMA so no one had to suffer the consequences of illegal pill production. But changes to social norms come ever so slowly!
At the same time we read that UK deaths from liver disease have doubled in recent years, and that the total alcohol-related deaths are set to reach 250,000 by 2031 if the current trends continue. All that for a drug that encourages egotistical feelings of anger and belligerence rather than inducing human empathy, selflessness and understanding.
But we can accept that kind of harm to society from a drug like alcohol, just make sure you’re not taking any illegal drugs kids!
Last week the Multidisciplinary Association of Psychedelic Studies (MAPS) held its 2010 Conference in San Jose, California – and the press stood up and took notice. It only took 40 years, but the government has finally given a few researchers permission to study the potential therapeutic uses of psychedelic drugs. Based on the preliminary results, it looks like mainstream science, and the media, are finally ready to move past the stigma of 1960s drug taking.
One of the more interesting articles is Can the Peace Drug Help Clean Up The War Mess? from Scientific American, reporting on the use of MDMA to treat war veterans suffering from post-traumatic stress disorder:
Brain-imaging studies in healthy volunteers show that MDMA quiets the amygdala, an almond-shaped structure deep in the brain that some researchers call a “fear center” due to its central role in triggering strong negative emotions. MDMA also releases a flood of the brain messengers serotonin and dopamine while increasing blood levels of the hormones oxytocin and prolactin, which promote social bonding. This potent mix diminishes fear and defensiveness and boosts empathy and the desire to connect with others, says Holland, so “the therapy work goes faster and deeper.”
For anyone interested in the use of psychedelics pre-Timothy Leary, I highly recommend this National Film Board of Canada documentary:
This documentary offers a compassionate, open-minded look at LSD and how it fits into our world. Long before Timothy Leary urged ageneration to “tune in, turn on and drop out,” the drug was hailed as a way to treat forms of addiction and mental illness. At the same time, it was being touted as a powerful tool for mental exploration and self-understanding.
A long time coming, but I think we’re about to conquer the final frontier: the human mind.
Last night I had the pleasure of attending UK ex-chief drug advisor David Nutt’s lecture here in London at the Hub Islington, one of a dozen such Hub communities that bring together people working for social change across the globe.
David Nutt was fired for standing up for scientific evidence that showed, for example, that ecstasy, cannabis, and LSD are less dangerous than alcohol. Or that more people die falling off horses every year than taking ecstasy (see his article on Equasy vs Ecstasy.) But it didn’t take long for Professor Nutt to get back on his feet: he’s just started the new Independent Council on Drug Harms with some of the top scientists in the field, which will rival the government’s Advisory Council on the Misuse of Drugs.
The most crucial data that the government doesn’t want to deal with appears in the graph below, from the 2007 Lancet article ‘Development of a Rational Scale to Assess the Harm of Drugs of Potential Misuse’:
The paper, co-authored by Prof Blakemore and Prof David Nutt, et al. , ‘presents a scale of harms based on three scales – physical harm, dependence and social harm – which were independently assessed by two groups of experts from the fields of chemistry, pharmacology, forensic science, psychiatry and other medical specialties.’
There was a surprisingly poor correlation between drugs’ class according to the Misuse of Drugs Act and their actual harm scores. Alcohol, ketamine, tobacco, and solvents (all unclassified at the time of assessment) were ranked as more harmful than LSD and ecstasy (class A drugs).
It’s obvious that something’s wrong here.
Professor Nutt talked about politicians feeling the pressure to be tough on drugs – but it turns out that at the time cannabis was reclassified as a Class B drug, two thirds of the public wanted cannabis to remain Class C or less. Maybe one of the answers is that we the public need to be more vocal in our desire for drug policy reform.
During the lecture at times I believe many of us didn’t know whether to laugh or cry, like when we read MP Vernon Coaker’s statement that “We look for evidence to support our policy decisions.” Surely it should be the other way around?
Last but not least is media bias. Scottish graduate Alasdair J M Forsyth wrote his PhD having looked at every single newspaper report of drug deaths in Scotland from 1990 to 1999 and then compared them with the coroners’ data. Check out the results below:
Out of the 2,255 drug deaths that decade, only certain drugs tended to attract media attention. 1 out of 265 involving paracetamol, 1 out of 72 involving morphine, 1 out of 48 involving diazepam – the media were clearly not interested in these drugs. They were more interested in cocaine (8:1), amphetamines (3:1) and heroin (5:1). But unbelievably, out of the 28 deaths from ecstasy in ten years, 26 were reported, meaning a near 1:1 ratio. An astounding bias.
Professor Nutt also pointed out that cannabis is not on this chart because cannabis doesn’t kill – you cannot die of a cannabis overdose. Of course alcohol is also missing off that list. Alcohol alone will have killed between 2000-3000 people in Scotland in that same decade – the same as all the other drugs combined. Makes you wonder why it is we consider alcohol in a separate category from the drugs we classify due to their potential harm.
One final example of how even some scientific reporting about drugs is biased. A study that made front page headlines claiming that ‘ecstasy fries your brain’ was later quietly retracted when the researchers realized they had given their subjects methamphetamine instead of ecstasy. Oops!
‘Distorted? a quantitative exploration of drug fatality reports in the popular press’
A Forsyth
International Journal of Drug Policy, Volume 12, Issue 5, Pages 435-453